Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Three-dimensional high-content imaging of unstained soft tissue with subcellular resolution using a laboratory-based X-ray microscope.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Dynamic laboratory x-ray phase-contrast microtomography with structure-based prior regularisation.

Measurement science & technology·2025
Same author

On the applicability of x-ray strain imaging using the edge illumination technique in biomedical applications.

Journal of physics D: Applied physics·2025
Same author

Edge-Illumination X-Ray Dark-Field Tomography.

Physical review applied·2025
Same author

Investigating gut alterations in Alzheimer's disease: In-depth analysis with micro- and nano-3D X-ray phase contrast tomography.

Science advances·2025
Same author

Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids.

Nature medicine·2025

Related Experiment Video

Updated: Aug 4, 2025

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

14.5K

Modulation transfer function (MTF) evaluation for x-ray phase imaging system employing attenuation masks.

Glafkos Havariyoun1, Lorenzo Massimi1, Charlotte Hagen1

  • 1Department of Medical Physics and Bioengineering, University College London, WC1E 6BT, United Kingdom.

Physics in Medicine and Biology
|March 30, 2023
PubMed
Summary
This summary is machine-generated.

Attenuation masks enhance x-ray imaging spatial resolution by improving the Modulation Transfer Function (MTF). Skipped masks offer greater MTF improvements than non-skipped masks, benefiting quality control for new imaging systems.

Keywords:
attenuation masksedge illumination phase contrastmodulation transfer functionphase contrastx-ray phase contrast

More Related Videos

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator
08:39

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

9.9K
X-ray Beam Induced Current Measurements for Multi-Modal X-ray Microscopy of Solar Cells
10:16

X-ray Beam Induced Current Measurements for Multi-Modal X-ray Microscopy of Solar Cells

Published on: August 20, 2019

13.9K

Related Experiment Videos

Last Updated: Aug 4, 2025

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

14.5K
Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator
08:39

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

9.9K
X-ray Beam Induced Current Measurements for Multi-Modal X-ray Microscopy of Solar Cells
10:16

X-ray Beam Induced Current Measurements for Multi-Modal X-ray Microscopy of Solar Cells

Published on: August 20, 2019

13.9K

Area of Science:

  • Medical Imaging Physics
  • X-ray Imaging Technology

Background:

  • Attenuation masks can improve spatial resolution and phase sensitivity in x-ray imaging.
  • Edge Illumination x-ray phase contrast imaging (EI-XPCI) is a typical mask-based system.
  • Investigating mask performance without phase effects is crucial for understanding their impact on Modulation Transfer Function (MTF).

Purpose of the Study:

  • To investigate the Modulation Transfer Function (MTF) performance of an x-ray imaging system using attenuation masks, specifically in the absence of phase effects.
  • To compare the MTF of systems with non-skipped and skipped attenuation masks against a system without masks.
  • To validate experimental findings with simulations and resolution bar pattern images.

Main Methods:

  • Performed pre-sampled MTF measurements using an edge test target.
  • Tested the system with no masks, non-skipped masks, and skipped masks (alternating apertures).
  • Acquired images of a resolution bar pattern for visual comparison across setups.

Main Results:

  • Non-skipped masks improved the detector's inherent MTF at specific frequencies related to signal spill-out.
  • Skipped masks further enhanced MTF over a broader frequency range compared to non-skipped masks.
  • Experimental MTF measurements were consistent with simulation results and bar pattern images.

Conclusions:

  • Attenuation masks demonstrably improve MTF in x-ray imaging systems.
  • Skipped mask configurations offer superior MTF enhancement compared to non-skipped configurations.
  • Quantified MTF improvements provide a basis for modifying quality control tests for mask-based clinical imaging systems.