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Updated: Aug 4, 2025
11:04
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis
Published on: February 19, 2013
26.5K
[Digestive infectious pathology: Diagnoses not to be missed]
Édouard Guenzi1, Ruiqian Chen1, Aurélie Sannier1
1Département de pathologie, hôpital Bichat Claude-Bernard, 46, rue Henri-Huchard, 75018 Paris, France.
Annales De Pathologie
|March 30, 2023
Summary
Pathologists are increasingly focused on gastrointestinal infectious diseases, particularly rare bacterial and parasitic infections. This review highlights diagnostic challenges and essential techniques for identifying these difficult-to-diagnose digestive tract pathologies.
Area of Science:
- Gastroenterology
- Pathology
- Infectious Diseases
Context:
- The COVID-19 pandemic has heightened interest in infectious diseases.
- Gastrointestinal infections present diagnostic challenges due to non-specific symptoms and normal endoscopic findings.
- Systematic biopsies are crucial for diagnosing obscure gastrointestinal pathologies.
Purpose:
- To review rare or difficult-to-diagnose bacterial and parasitic pathologies of the digestive tract.
- To emphasize the importance of histopathological analysis, special stains, and immunohistochemistry.
- To guide pathologists in identifying "not to be missed" infectious agents in the GI tract.
Summary:
- This article discusses the diagnosis of infectious gastrointestinal diseases, focusing on challenging bacterial and parasitic cases.
- It details the utility of special stains and immunohistochemical analyses for accurate identification.
- Key pathologies requiring careful histopathological evaluation are presented.
Impact:
- Aids pathologists in accurately diagnosing uncommon gastrointestinal infections.
- Improves patient outcomes by ensuring timely and correct identification of pathogens.
- Enhances diagnostic capabilities for infectious diseases within the digestive system.
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