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Cyclic oscillations in melanization within Hystrix porcupine quills

Thomas P Dooley1, Sydney Anderson2, Shosuke Ito3

  • 1Trends in Pharma Development LLC, Pinson, Alabama, USA.

Pigment Cell & Melanoma Research
|April 1, 2023
PubMed
Abstract

No abstract available in PubMed .

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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