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Updated: Aug 4, 2025
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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
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Radionuclide Tracers for Myocardial Perfusion Imaging and Blood Flow Quantification
Teresa Mannarino1, Roberta Assante1, Adriana D'Antonio1
1Department of Advanced Biomedical Sciences, University Federico II, Via Sergio Pansini 5, Naples 80131, Italy.
Cardiology Clinics
|April 1, 2023
Summary
Nuclear cardiology uses myocardial perfusion imaging to diagnose and manage coronary artery disease. This review covers current radiotracers, technological advances, and future applications for improved patient care.
Area of Science:
- Cardiovascular Imaging
- Nuclear Medicine
- Radiopharmaceutical Science
Background:
- Myocardial perfusion imaging is a cornerstone in diagnosing and managing coronary artery disease (CAD).
- Various radiopharmaceuticals are available for single-photon emission computed tomography (SPECT) and positron emission tomography (PET) modalities.
- Each tracer possesses unique advantages and limitations influencing imaging protocols.
Purpose of the Study:
- To review the current state-of-the-art radiotracers for myocardial perfusion imaging.
- To discuss advancements in blood flow quantification techniques.
- To highlight emerging technologies and potential future applications in the field.
Main Methods:
- Comprehensive literature search on myocardial perfusion imaging radiotracers.
- Analysis of SPECT and PET radiopharmaceutical characteristics.
- Review of recent technological innovations and clinical studies.
Main Results:
- Detailed overview of commonly used and novel radiotracers for myocardial perfusion imaging.
- Comparison of tracer performance regarding diagnostic accuracy and quantification capabilities.
- Identification of technologic progress enhancing imaging resolution and accuracy.
Conclusions:
- Radiotracer selection is critical for optimal myocardial perfusion imaging outcomes.
- Technological advancements are continuously improving the diagnostic power of nuclear cardiology.
- Future research directions focus on novel tracers and expanded clinical applications for CAD management.
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