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Pomegranate and Cognitive Performance: A Systematic Review.
Roghayeh Molani-Gol1,2, Elaheh Foroumandi3, Mohammad Alizadeh2
1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Current Pharmaceutical Design
|April 3, 2023
Summary
Pomegranate consumption shows a positive link to improved cognitive function. Including pomegranate in your diet may help reduce the risk of cognitive impairment.
Area of Science:
- Neuroscience
- Nutritional Science
Background:
- Cognitive dysfunction, including dementia, is a prevalent neurological disorder impacting memory and problem-solving.
- Nutritional factors are increasingly recognized for their potential role in neurodegenerative disease prevention.
Approach:
- A systematic review was conducted to assess the relationship between pomegranate intake and cognitive function.
- Searched PubMed, Embase, Google Scholar, and Scopus for animal and human studies up to July 2021.
- Evaluated 24 studies (20 animal, 4 RCTs) for quality and bias using OHAT and Cochrane tools.
Key Points:
- All included studies indicated a positive association between pomegranate treatment and enhanced cognitive function.
- Pomegranate intake demonstrated benefits across various cognitive domains in both animal models and human trials.
- The review synthesized evidence from a comprehensive literature search and rigorous quality assessment.
Conclusions:
- Pomegranate treatment is demonstrably linked to improvements in cognitive function.
- Daily pomegranate consumption may offer a strategy for lowering cognitive impairment risk at a population level.
- Further research could explore specific mechanisms and optimal dosages for cognitive benefits.
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