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Related Experiment Video

Updated: Aug 4, 2025

Studying Orthodontic Tooth Movement in Mice
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[Research progress in immunomodulation in orthodontic tooth movement].

K J Zhang1, H W Zhang2, B Yan1

  • 1Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University & Jiangsu Province Key Laboratory of Oral Diseases & Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing 210029, China.

Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology
|April 3, 2023
PubMed
Summary

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The immune system, through cytokines and cell interactions, influences bone remodeling during orthodontic tooth movement. This review explores immunomodulation

Area of Science:

  • Immunology
  • Orthodontics
  • Cell Biology

Context:

  • Orthodontic tooth movement involves complex bone remodeling processes.
  • The role of the immune system in this process is gaining significant attention.

Purpose:

  • To review the current research on immunomodulation in orthodontic tooth movement.
  • To discuss the biological mechanisms involving immune cells and cytokines.

Summary:

  • Cytokine secretion and immune cell interactions regulate osteoclast and osteoblast differentiation during tooth movement.
  • This article synthesizes research on the immune system's impact on orthodontic bone remodeling.

Impact:

  • Provides a comprehensive understanding of the biological mechanisms underlying orthodontic treatment.

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  • Highlights the potential for future research in immunomodulation for orthodontics.