Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Disruption of Pik3r1 promotes muscle hyperplasia and lipolysis in grass carp (Ctenopharyngodon idella).

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026

Same author

A Spatially Resolved Atlas of Alternative Polyadenylation Across 18 Human Tissues and 76 Disease States.

Genomics, proteomics & bioinformatics·2026

Same author

Morphological characterization and RNA sequencing reveal adaptive strategies of <i>Coix lacryma</i>-<i>jobi</i> L. under waterlogging stress during the jointing stage.

PeerJ·2026

Same author

[Effect of simultaneous multi-plane surgery on cardiopulmonary function in patients with obstructive sleep apnea-hypopnea syndrome and its curative effect].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery·2025

Same author

Plant food-derived antioxidant nutrients in neuroprotection against chemotherapy-induced neurotoxicity: from molecular mechanisms to clinical applications.

Frontiers in nutrition·2025

Same author

Food-Herb Dual-Function in Astragali Radix-Poria-Rheum: Network Pharmacology and Database Mining for Diabetic Kidney Disease Mechanisms Exploration.

Food science & nutrition·2025

Same journal

GALNT7 promotes the malignant progression of gastrointestinal stromal tumors by regulating KIT O-GalNAc glycosylation.

Precision clinical medicine·2026

Same journal

Protein modification systems as cancer biomarkers and therapeutic targets.

Precision clinical medicine·2026

Same journal

Trispecific antibodies: is more always better? Advances and boundaries.

Precision clinical medicine·2026

Same journal

Calming sterile inflammation in intervertebral disc degeneration: taurine disrupts mitochondria-cGAS-STING signaling via autophagy enhancement.

Precision clinical medicine·2026

Same journal

JS-K induces autophagy-dependent ferroptosis in bladder cancer: a multimodal mechanistic and translational study.

Precision clinical medicine·2026

Same journal

Circular RNA as emerging precision therapeutics: from RNA regulation to peptide translation.

Precision clinical medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 4, 2025

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces

Published on: March 1, 2017

GLUE multimodal single cell data.

Weizhong Li¹, Chaoyu Yan¹

¹Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.

Precision Clinical Medicine

|April 3, 2023

Summary

This summary is machine-generated.

This commentary discusses graph-linked embedding for integrating multi-omics single-cell data. It highlights the method's potential for advancing regulatory network inference in complex biological systems.

More Related Videos

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

Related Experiment Videos

Last Updated: Aug 4, 2025

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces

Published on: March 1, 2017

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

Area of Science:

Bioinformatics
Computational Biology
Genomics

Background:

Single-cell multi-omics data integration presents challenges.
Regulatory network inference is crucial for understanding cellular function.
Existing methods may not fully capture complex biological relationships.

Purpose of the Study:

To provide a commentary on a novel method for multi-omics single-cell data integration.
To discuss the application of graph-linked embedding for regulatory inference.
To evaluate the implications of this approach for systems biology.

Main Methods:

Commentary on a graph-linked embedding approach.
Discussion of multi-omics data integration strategies.
Analysis of regulatory inference techniques.

Main Results:

The commentary evaluates the strengths of graph-linked embedding for single-cell data.
It discusses the method's utility in inferring gene regulatory networks.
Potential applications in various biological contexts are explored.

Conclusions:

Graph-linked embedding offers a promising framework for multi-omics integration.
This approach can enhance the accuracy of regulatory network inference.
The commentary underscores the importance of advanced computational tools in systems biology.