Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Harmonizing the genetic counselor profession in Europe.

European journal of human genetics : EJHG·2026

Same author

Cascade counselling and testing. Recommendations of the European Society of Human Genetics.

European journal of human genetics : EJHG·2025

Same author

Reflectance mapping with microsphere-assisted white light interference nanoscopy.

Scientific reports·2024

Same author

Study of factors affecting the magnetic sensing capability of shape memory alloys for non-destructive evaluation of cracks in concrete: Using response surface methodology (RSM) and artificial neural network (ANN) approaches.

Heliyon·2024

Same author

i-Dent: A virtual assistant to diagnose rare genetic dental diseases.

Computers in biology and medicine·2024

Same author

Robust, high-yield, rapid fabrication of DNA constructs for Magnetic Tweezers.

Biochemical and biophysical research communications·2024

Same journal

Impact of an Artificial Albumin Corona on Surface Charge-Driven Nano-Bio Interactions and Cytotoxicity of Silver Nanoparticles.

ACS omega·2026

Same journal

Structural and Functional Disruption of Thiopurine S‑Methyltransferase by the A80P Variant: A Simulation and Genotyping Study.

ACS omega·2026

Same journal

CRISPR/Cas12a2-Mediated Ultrasensitive Assay for Rapid Detection of H1N1 Influenza Virus RNA.

ACS omega·2026

Same journal

Photocatalytic Treatment of Real Sugar Industry Wastewater Using Lignocellulosic Biomass-Derived Hydrochar/g-CN.

ACS omega·2026

Same journal

Electrochemical Dopamine Biosensor Based on Plant-Derived Peroxidase Immobilized on Titanate Nanowires.

ACS omega·2026

Same journal

Revealing the Effects of Process Parameters on Structural, Thermal, Mechanical, Biodegradation, and Biocompatibility Properties on the Electrospinning of Poly(vinyl alcohol)/Microbial Inulin Nanofibers.

ACS omega·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 4, 2025

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Published on: June 27, 2022

Characterization of Functional Materials Using Coherence Scanning Interferometry and Environmental Chambers.

Paul C Montgomery¹, Manuel Flury¹, Freddy Anstotz¹

¹Laboratoire des Sciences de l'Ingénieur de l'Informatique et de l'Imagerie (ICube), University of Strasbourg - CNRS - INSA, 300 Boulevard Sébastien Brant, Illkirch 67412, France.

|April 3, 2023

Summary

This summary is machine-generated.

Interference microscopy now characterizes complex functional materials. Advanced techniques like 4D microscopy and environmental chambers enable detailed analysis of small structures and inhomogeneous materials.

More Related Videos

Characterization of Surface Modifications by White Light Interferometry: Applications in Ion Sputtering, Laser Ablation, and Tribology Experiments

Characterization of Surface Modifications by White Light Interferometry: Applications in Ion Sputtering, Laser Ablation, and Tribology Experiments

Published on: February 27, 2013

Characterizing Dissipative Elastic Metamaterials Produced by Additive Manufacturing

Characterizing Dissipative Elastic Metamaterials Produced by Additive Manufacturing

Published on: June 28, 2024

Related Experiment Videos

Last Updated: Aug 4, 2025

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Published on: June 27, 2022

Characterization of Surface Modifications by White Light Interferometry: Applications in Ion Sputtering, Laser Ablation, and Tribology Experiments

Characterization of Surface Modifications by White Light Interferometry: Applications in Ion Sputtering, Laser Ablation, and Tribology Experiments

Published on: February 27, 2013

Characterizing Dissipative Elastic Metamaterials Produced by Additive Manufacturing

Characterizing Dissipative Elastic Metamaterials Produced by Additive Manufacturing

Published on: June 28, 2024

Area of Science:

Materials Science
Optical Metrology
Surface Science

Background:

Interference microscopy, initially for static surfaces, now measures diverse samples.
Characterizing functional materials with small structures and inhomogeneities is challenging.
Traditional methods struggle with dynamic and complex material properties.

Purpose of the Study:

To review advancements in interference microscopy for functional materials characterization.
To present novel techniques extending the capabilities of interference microscopy.
To demonstrate the application of these techniques to challenging material systems.

Main Methods:

4D microscopy for real-time topographic measurements of dynamic surfaces.
High-resolution tomography for transparent layer characterization.
Local spectroscopy for measuring optical properties of small areas.
Environmental chambers for controlled measurements (pressure, temperature, humidity, deposition, immersion).
Use of glass microspheres to enhance lateral resolution.

Main Results:

Demonstrated real-time surface measurement of moving samples.
Successfully characterized transparent layers and local optical properties.
Quantified mechanical and drying properties of polymers under controlled conditions.
Studied colloidal layer behavior in aqueous environments with pollutants.
Achieved improved lateral resolution using glass microspheres.

Conclusions:

Interference microscopy is a versatile tool for functional materials.
Advanced techniques significantly enhance the characterization of small and inhomogeneous structures.
The reviewed methods provide comprehensive insights into material properties and behavior.