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Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

18
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
18
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

94
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
94
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

41
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
41
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

27
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
27
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

19
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
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Related Experiment Video

Updated: Aug 4, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

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Evolving Coronary Stent Technologies - A Glimpse Into the Future.

Smeet Patel1, Kalpen B Patel2, Zeel Patel1

  • 1Medicine, New York University School of Global Public Health, New York City, USA.

Cureus
|April 3, 2023
PubMed
Summary
This summary is machine-generated.

Coronary stents have evolved significantly for treating artery disease, but challenges like thrombosis remain. Future innovations like gene-eluting stents and 4D-printed customized stents show promise for optimal coronary stent devices.

Keywords:
coronary artery diseasesgene-eluting stentsin-stent restenosisstent optimizationstent sensorsstents

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Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
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4D Printed Bifurcated Stents with Kirigami-Inspired Structures
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Related Experiment Videos

Last Updated: Aug 4, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
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4D Printed Bifurcated Stents with Kirigami-Inspired Structures
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Area of Science:

  • Cardiovascular medicine
  • Biomaterials engineering
  • Interventional cardiology

Background:

  • Coronary artery disease (CAD) treatment relies heavily on stent implementation.
  • Stent technology has advanced from bare-metal to drug-eluting, bioresorbable, and polymer-free designs.
  • Despite improvements, current stents face challenges including thrombosis and in-stent restenosis due to endothelial injury.

Purpose of the Study:

  • To review the evolution of coronary stent technologies.
  • To identify limitations of current coronary stents.
  • To explore future advancements for optimal coronary stent devices.

Main Methods:

  • Comprehensive evaluation of published studies on coronary stent evolution.
  • Literature review to identify inadequacies of existing stents.
  • Analysis of emerging stent technologies and their potential.

Main Results:

  • Coronary stents have improved clinical outcomes but persistent risks of thrombosis and restenosis exist.
  • Gene-eluting stents (GES) and customized stents with self-reporting sensors are emerging alternatives.
  • Novel 4D printing technologies offer potential for customized stent development.

Conclusions:

  • Future optimal coronary stent devices may incorporate gene-eluting capabilities and integrated self-reporting sensors.
  • 4D printing technology presents a pathway for customized coronary stents.
  • Further interventional evidence is crucial to validate the future prospects of these advanced stent innovations.