Feasibility of aortic aneurysm sac embolization using a novel shape memory polymer embolic device

Area of Science:

• Biomaterials Science
• Medical Devices
• Vascular Surgery

Background:

• Endovascular Aneurysm Repair (EVAR) is a common treatment for aortic aneurysms.
• Aneurysm sac embolization aims to reduce stress on the graft and prevent complications.
• Novel embolic materials are needed to improve EVAR outcomes.

Purpose of the Study:

• To investigate the feasibility and safety of using a novel self-expanding porous shape memory polymer (SMP) device for aneurysm sac embolization.
• To evaluate the impact of SMP device implantation on aneurysm sac volume and associated complications during EVAR.

Main Methods:

• Retrospective analysis of 18 patients undergoing EVAR with SMP device implantation between January 2019 and July 2021.
• SMP devices were implanted into the aneurysm sac immediately after endograft placement.
• Follow-up included assessment of technical success, aneurysm volume changes, and complications at 7 days, and 3, 6, and 12 months.

Main Results:

• 100% technical success rate for SMP device deployment.
• Significant reduction in aneurysm sac volume (mean -30 mL, p < 0.001) observed at a mean follow-up of 11 months.
• Aneurysm sac regression occurred in all evaluable patients, even in the presence of endoleaks, with no treatment-related morbidity or mortality.

Conclusions:

• Self-expanding porous shape memory polymer (SMP) devices are feasible and safe for aortic aneurysm sac embolization during EVAR.
• This novel embolic strategy demonstrates promising results in achieving aneurysm sac regression.
• Further prospective studies are warranted to confirm these findings.