Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cerebral vascular diameter and flow irregularities due to ischemic stroke after middle cerebral artery occlusion.

American journal of physiology. Heart and circulatory physiology·2026
Same author

Quality of life after tranexamic acid in subarachnoid hemorrhage: post-hoc analysis of the ULTRA trial.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same author

Mapping the mRS Into the EQ-5D-5L in Patients With Ischemic Stroke.

Stroke·2026
Same author

Identifying myocardial regions perfused by coronary arteries through detailed human microvasculature data.

Computers in biology and medicine·2026
Same author

CTP-Free Method for Automated Lesion Water Uptake in Acute Ischemic Stroke.

AJNR. American journal of neuroradiology·2026
Same author

Validation and simplification of the MR PREDICTS @24H model for outcome prediction after endovascular thrombectomy for acute ischemic stroke.

International journal of stroke : official journal of the International Stroke Society·2026

Related Experiment Video

Updated: Aug 4, 2025

Simulator Training for Endovascular Neurosurgery
08:08

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

3.7K

Microcatheter tracking in thrombectomy procedures: A finite-element simulation study.

Nerea Arrarte Terreros1, Silvia Renon2, Francesca Zucchelli2

  • 1Department of Biomedical Engineering and Physics, Amsterdam UMC, Location University of Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location University of Amsterdam, Amsterdam, the Netherlands.

Computer Methods and Programs in Biomedicine
|April 3, 2023
PubMed
Summary

Realistic in-silico thrombectomy models require accurate microcatheter tracking. A new tip-dragging method better simulates microcatheter-vessel interaction, impacting thrombus stress and fragmentation during mechanical thrombectomy.

Keywords:
Acute ischemic strokeFinite element analysisStent-retrieverThrombectomy

More Related Videos

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke
09:00

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Published on: February 10, 2023

1.3K
Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging
11:27

Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging

Published on: April 4, 2013

12.5K

Related Experiment Videos

Last Updated: Aug 4, 2025

Simulator Training for Endovascular Neurosurgery
08:08

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

3.7K
Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke
09:00

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Published on: February 10, 2023

1.3K
Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging
11:27

Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging

Published on: April 4, 2013

12.5K

Area of Science:

  • Biomedical Engineering
  • Computational Fluid Dynamics
  • Medical Imaging

Background:

  • Mechanical thrombectomy is crucial for acute ischemic stroke.
  • In-silico models aid in studying thrombectomy success and failure.
  • Realistic modeling of microcatheter tracking is essential for effective simulations.

Purpose of the Study:

  • To present a novel approach for modeling microcatheter tracking during mechanical thrombectomy.
  • To compare a new tip-dragging method with a centerline method for microcatheter simulation.
  • To evaluate the impact of tracking methods on simulated thrombectomy outcomes and thrombus stress.

Main Methods:

  • Finite-element simulations were performed on 3 patient-specific vessel geometries.
  • Two microcatheter tracking methods were simulated: centerline and tip-dragging.
  • Simulations were qualitatively validated against digital subtraction angiography (DSA) images.

Main Results:

  • The tip-dragging method provided a more realistic simulation of microcatheter-vessel wall interaction compared to DSA.
  • Simulated thrombus retrieval success rates were similar between methods.
  • Significant differences in thrombus stress fields (up to 84% in maximum principal stress) were observed between the two tracking methods.

Conclusions:

  • Microcatheter positioning significantly influences thrombus stress fields during simulated retrieval.
  • These stress field variations may impact thrombus fragmentation and retrieval outcomes in in-silico thrombectomy models.
  • The tip-dragging method offers a more realistic simulation for studying mechanical thrombectomy mechanics.