[Hymenoptera venom allergy: what's new in 2023]

Area of Science:

• Allergology and Immunology
• Clinical Medicine

Background:

• Hymenoptera venom allergy presents significant challenges in allergology.
• Recent shortages of specific venom products necessitate revised diagnostic and therapeutic strategies in Switzerland.

Approach:

• This review synthesizes current diagnostic methodologies, including recombinant serologies.
• It examines updated recommendations for screening indolent systemic mastocytosis.
• Various immunotherapy protocols for venom desensitization are discussed.

Key Points:

• Recombinant serologies offer advanced diagnostic capabilities for Hymenoptera venom allergy.
• Screening for indolent systemic mastocytosis requires updated guidelines.
• Immunotherapy protocols involve both aqueous and aluminum hydroxide-adsorbed purified venoms.

Conclusions:

• Adapting diagnostic and therapeutic approaches is crucial for managing Hymenoptera venom allergy effectively.
• The review provides a comprehensive overview of current practices and future directions in venom allergy management.