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Updated: Aug 4, 2025

Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes
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Direct Lineage Reprogramming for Induced Keratinocyte Stem Cells: A Potential Approach for Skin Repair

Haohui Lin1, Yu Pan2, Sa Cai1

  • 1Department of Anatomy, Histology & Developmental Biology, Medical School, Shenzhen University, Shenzhen, People's Republic of China.

Stem Cells Translational Medicine
|April 5, 2023
PubMed
Summary

Directly reprogramming somatic cells into induced keratinocyte stem cells (iKSCs) offers a promising solution for wound healing. This review explores lineage transcription factor-mediated reprogramming for generating iKSCs and discusses future skin repair applications.

Keywords:
direct lineage reprogrammingepigeneticsin situ reprogramminginduced keratinocyte stem cellslineage reprogramming

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