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Ganoderma Spore Lipids Inhibit Perineural Invasion in Pancreatic Cancer by Downregulating NGF-TrkA Pathway

Haohui Lin1, Manhon Chung2, Yi Yang1

  • 1Laboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.

Journal of Evidence-Based Integrative Medicine
|July 8, 2025
PubMed
Summary

Ganoderma spore lipid (GSL) inhibits pancreatic cancer cell invasion by targeting the NGF-TrkA pathway. This study suggests GSL as a potential adjuvant therapy to prevent cancer recurrence.

Keywords:
Ganoderma spore lipidNGF–TrkA pathwaypancreatic cancerperineural invasion

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