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Multiscale model for blood flow after a bileaflet artificial aortic valve implantation
Marcin Nowak1, Eduardo Divo2, Wojciech P Adamczyk3
1Gdańsk University of Technology, Faculty of Civil and Environmental Engineering, Department of Mechanics of Materials and Structures, Poland.
Computers in Biology and Medicine
|April 5, 2023
Summary
This study presents a numerical model for blood flow through artificial aortic valves, crucial for understanding cardiovascular diseases. The model aids surgeons in planning virtual operations and predicting surgical outcomes for patients.
Area of Science:
- Biomedical Engineering
- Computational Fluid Dynamics
- Cardiovascular Science
Background:
- Cardiovascular diseases are a leading global cause of mortality, often linked to atherosclerosis.
- Artificial aortic valves are critical in managing cardiovascular conditions.
Purpose of the Study:
- To develop and validate a numerical model for blood flow through an artificial aortic valve.
- To assess the impact of valve motion and vessel compliance on cardiovascular dynamics.
Main Methods:
- Utilized an overset mesh approach to simulate artificial aortic valve leaflet motion.
- Integrated a lumped parameter model to account for cardiac system response and vessel compliance.
- Compared laminar, k-ϵ, and k-ω turbulence models for blood flow simulation.
Main Results:
- The numerical model accurately simulated artificial aortic valve dynamics and blood flow.
- The lumped parameter model significantly influenced outlet pressure predictions.
- The overset mesh approach effectively captured moving valve geometry effects.
Conclusions:
- The developed numerical model and protocol are suitable for virtual surgical planning on patient-specific vasculature.
- The time-efficient simulation procedure can support clinical decision-making and predict surgical outcomes.

