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Difference from Background: Limit of Detection

Difference from Background: Limit of Detection

The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...

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Related Experiment Video

Updated: Jul 4, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

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Published on: December 16, 2022

Correction: Comparison of deep learning-based denoising methods in cardiac SPECT

Antti Sohlberg^1,2, Tuija Kangasmaa³, Chris Constable⁴

¹Department of Clinical Physiology and Nuclear Medicine, Päijät-Häme Central Hospital, Lahti, Finland. antti.sohlberg@phhyky.fi.

|April 6, 2023

Summary

No abstract available in PubMed .

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