[Mathematic modeling of the processes of water and salt metabolism]

This paper describes mathematical modeling of fluid-electrolyte metabolism and fluid homeostasis in real and simulated microgravity. At the first stage physiological reactions to provocative tests were simulated. The assumptions made yielded satisfactory results, particularly with respect to the excretion of the most important electrolytes in different time intervals of bed rest and recovery. The development of models of fluid homeostasis, taking into consideration tissue elasticity and plasticity and fluid buffering capacity, is discussed.