Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Upper Respiratory Drugs: Decongestants

Upper Respiratory Drugs: Decongestants

Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Acute Pharyngitis

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:

Tonsillitis II: Management

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.

Tonsillitis I: Introduction

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bilateral Spontaneous Dissection of the Superficial Femoral Arteries (SFAs): A Case Report.

Cureus·2025

Same author

Subclavian Venous Spasm During Pacemaker Implantation: A Case Report.

Cureus·2025

Same author

Coronary Slow Flow Phenomenon: A Narrative Literature Review.

Cureus·2025

Same author

Literature Review of Venous Spasm During Pacemaker Implantation.

Cureus·2025

Same author

Ranolazine as a First-Choice Anti-anginal Medication for Patients With Coronary Artery Ectasia: A Case Series.

Cureus·2024

Same author

Surprising Resolution of Life-Long Severe Generalized Hyperhidrosis Post-angioplasty and Stenting.

Cureus·2024

Same journal

Immunohistochemistry (IHC) Versus Genomic Profiling in Cancer: Roles in Precision Medicine.

Cureus·2026

Same journal

Pediatric Nasal Tip Reconstruction After a Donkey Bite Using an Expanded Paramedian Forehead Flap With Conchal Cartilage Grafts: A Case Report.

Cureus·2026

Same journal

Splenic Rupture: A Delayed and Rare Complication of Colonoscopy.

Cureus·2026

Same journal

Super-refractory Status Epilepticus in Febrile Infection-Related Epilepsy Syndrome Triggered by Influenza A: A Pediatric Case Report.

Cureus·2026

Same journal

Comparative Evaluation of Serum Peroxiredoxin 2 (PRDX2), Serum Peroxiredoxin 4 (PRDX4), and Plasma Methylated Septin 9 (mSEPT9) Levels Against Conventional Biomarkers for Early Detection of Colorectal Cancer: A Study Protocol.

Cureus·2026

Same journal

Inspiratory Muscle Training for Patients With Chronic Obstructive Pulmonary Disease: A Narrative Review.

Cureus·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 4, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Primary Cough Headache: A Case Report.

Khudheeja A Ahmed¹, Juwayria A Ahmed¹, Ibrahim Mohsin²

¹Research, KAAJ Healthcare, San Jose, USA.

|April 7, 2023

Summary

This summary is machine-generated.

Primary cough headache (PCH) can evolve, presenting with atypical triggers beyond coughing and lasting longer than usual. This case highlights PCH

Keywords:

case report evolution of symptoms indomethacin primary cough headache valsalva maneuver

More Related Videos

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Related Experiment Videos

Last Updated: Aug 4, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Area of Science:

Neurology
Headache Medicine

Background:

Primary cough headache (PCH) is defined by headaches triggered by Valsalva maneuvers.
PCH typically presents as sudden, bilateral headaches lasting minutes to two hours.

Observation:

A 53-year-old female experienced PCH with unusually prolonged headache episodes lasting several hours.
Headache triggers evolved from coughing to unassociated with Valsalva maneuvers, and eventually to no discernible trigger.
Diagnostic imaging, including MRI and CT, ruled out secondary causes.

Findings:

The patient was treated with indomethacin, topiramate, and metoprolol tartrate.
This treatment regimen effectively reduced headache intensity and duration.
Symptoms resolved within four weeks.

Implications:

This case expands the understanding of PCH's potential trigger evolution and atypical presentations.
It underscores the importance of considering PCH even with prolonged headache durations and varied triggers.
The successful treatment demonstrates a viable therapeutic approach for complex PCH cases.