Related Experiment Video
Updated: Aug 3, 2025

Growth of Mycobacterium tuberculosis Biofilms
Published on: February 15, 2012
Profiling Mycobacterium ulcerans: sporulation, survival strategy and response to environmental factors
Eunice Ampadubea Ayerakwa1,2, Molly Kukua Abban1,2, Abiola Isawumi1,2
1West African Centre for Cell Biology of Infectious Pathogens, LG 54 Volta Road, University of Ghana, Legon Accra, Ghana.
Abstract:
Mycobacterium ulcerans is the causative agent of Buruli ulcer - a necrotizing skin infection. As an environmental pathogen, it has developed stress response mechanisms for survival. Similar to endospore formation in M. marinum, it is likely that M. ulcerans employs sporulation mechanisms for its survival and transmission. In this review, we modeled possible transmission routes and patterns of M. ulcerans from the environment to its host. We provided insights into the evolution of M. ulcerans and its genomic profiles. We discuss reservoirs of M. ulcerans as an environmental pathogen and its environmental survival. We comprehensively discuss sporulation as a possible stress response mechanism and modelled endospore formation in M. ulcerans. At last, we highlighted sporulation associated markers, which upon expression trigger endospore formation.
More Related Videos
Related Concept Videos
Endospores and Sporulation
Gene Regulation During Sporulation
Stringent Response in E. coli
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Bacterial Phylum Actinobacteria

