Anesthetic Concerns during Gamma-Knife Radiosurgery.
Manjul Tripathi1, Rajeev Chauhan2, Ankur Luthra2
1Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Neurology India
|April 7, 2023
Summary
Anesthesia management is crucial for Gamma Knife radiosurgery (GKRS), especially for pediatric and anxious patients. This approach ensures patient immobilization and a smooth treatment course for neurosurgical conditions.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Anesthesiology
Background:
- Gamma Knife radiosurgery (GKRS) is a primary treatment for numerous neurosurgical conditions.
- Over 1.2 million patients globally have undergone GKRS, with expanding indications.
Purpose of the Study:
- To outline anesthetic considerations for Gamma Knife radiosurgery across diverse age groups.
- To present an effective management strategy based on extensive clinical experience.
Main Methods:
- Review of anesthetic management for 2526 patients undergoing frame-based GKRS over 11 years.
- Focus on strategies for pediatric, mentally challenged, and anxious adult patients.
Main Results:
- Pediatric (n=76) and mentally challenged adults (n=12) require special attention due to potential issues with frame fixation, imaging, and claustrophobia.
- Anxiety, fear, and claustrophobia in adults often necessitate sedation or anesthesia.
Conclusions:
- Key goals include painless frame fixation, immobility during treatment, and a comfortable post-procedure recovery.
- Anesthesia ensures patient immobilization and accessibility for neurosurgical procedures during GKRS.
Related Concept Videos
Parenteral Anesthetics: Overview
171
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
171
General Anesthesia: Overview
255
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
255
Inhalational Anesthetics: Overview
377
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
377
Radiological Investigation III: Pulmonary Angiogram and PET Scan
131
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
131
Local Anesthetics: Adverse Effects
469
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
469
Imaging Studies I: CT and MRI
352
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
352


