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Updated: Aug 3, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Normal and Variant Sinonasal Anatomy.

Richard D Beegle1, John V Murray2, Sukhwinder Johnny S Sandhu2

  • 1AdventHealth Medical Group, 2600 Westhall Lane, 4th Floor, Maitland, FL 32751, USA.

Oral and Maxillofacial Surgery Clinics of North America
|April 9, 2023
PubMed
Summary
This summary is machine-generated.

Understanding complex paranasal sinus anatomy and its variants is crucial for effective treatment and surgical safety. This review highlights key anatomical variations to prevent complications.

Keywords:
Anatomic variantsComputed tomography (CT)Functional endoscopic sinus surgery (FESS)Paranasal sinuses

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Area of Science:

  • Otolaryngology
  • Medical Imaging
  • Surgical Anatomy

Background:

  • The paranasal sinuses exhibit intricate anatomy with numerous variations.
  • These anatomical differences can increase susceptibility to sinonasal diseases.
  • Familiarity with these variations is essential for clinicians.

Purpose of the Study:

  • To provide a comprehensive review of paranasal sinus anatomy.
  • To emphasize clinically significant anatomical variants.
  • To enhance understanding for improved patient outcomes.

Main Methods:

  • Review of anatomical literature.
  • Emphasis on surgical implications.
  • Categorization of common and uncommon variants.

Main Results:

  • Detailed description of standard paranasal sinus anatomy.
  • Identification and illustration of multiple anatomical variants.
  • Discussion of how variants impact disease predisposition and surgical approaches.

Conclusions:

  • Mastery of paranasal sinus anatomy and its variants is vital for successful surgical interventions.
  • Awareness of anatomical variations aids in preventing intraoperative complications.
  • This knowledge supports safer and more effective management of sinonasal conditions.