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[Use of citicoline in high dosages in acute cerebrovascular disease]

Minerva Medica
|March 17, 1986
PubMed

Insights

Large doses of citicoline effectively treated acute cerebrovascular disturbances in 30 patients. This treatment resolved both mental impairments and focal neurological deficits.

Area of Science:

  • Neuroscience
  • Pharmacology

Context:

  • Acute cerebrovascular disturbances represent a significant cause of morbidity and mortality.
  • Neurological deficits and mental disturbances are common sequelae of cerebrovascular events.

Purpose:

  • To evaluate the efficacy of high-dose citicoline in patients with acute cerebrovascular disturbances.
  • To assess the impact of citicoline on both cognitive and motor functions following a stroke.

Summary:

  • A study involving 30 patients with acute cerebrovascular disturbances investigated the therapeutic effects of high-dose citicoline (1 g).
  • The administration of citicoline demonstrated significant effectiveness in alleviating mental disturbances.
  • Furthermore, the treatment successfully resolved focal neurological deficits associated with the cerebrovascular event.

Impact:

  • Citicoline shows promise as a therapeutic agent for managing acute cerebrovascular conditions.
  • This research suggests a potential role for citicoline in improving recovery outcomes for stroke patients.

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