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Murine Fetal Echocardiography
Published on: February 15, 2013
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To investigate the correlation between normal fetal biventricular myocardial function and gestational age using
Min Hou1, Xiao-Jing Duan1, Yan An2
1Department of Ultrasonography, Affiliated Hospital of Hebei University, Baoding, China.
Frontiers in Cardiovascular Medicine
|April 10, 2023
Summary
Fetal ventricular myocardial velocity decreases from base to apex. Global peak myocardial velocity in fetuses increases with gestational age, unlike strain and strain rate, suggesting constant ventricular deformability.
Area of Science:
- Cardiology
- Fetal Medicine
- Medical Imaging
Background:
- Assessing fetal cardiac function is crucial for prenatal care.
- Velocity vector imaging (VVI) offers advanced insights into myocardial mechanics.
Purpose of the Study:
- To evaluate fetal left and right ventricular myocardial function using VVI.
- To explore the relationship between global myocardial function and gestational age.
Main Methods:
- 127 normal fetuses were grouped by gestational age.
- Velocity vector imaging measured segmental and global ventricular velocity, strain, and strain rate.
- Analyzed trends and correlations of myocardial function parameters with gestational age.
Main Results:
- Fetal ventricular peak velocities decreased from base to apex (P<0.05).
- Global peak ventricular velocity positively correlated with gestational age (moderate correlation).
- Fetal ventricular strain and peak strain rate did not significantly correlate with gestational age.
Conclusions:
- Fetal myocardial velocity exhibits a base-to-apex gradient.
- Global peak myocardial velocity is linearly associated with gestational age.
- Fetal ventricular myocardial deformability remains consistent during mid-to-late gestation.
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