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Intracranial Myroides odoratimimus Infection After EVD Successfully Treated with Intravenous Plus Intraventricular
Ling-Zhi Jiang1, Ye Shen1, Feng Liang1
1Center for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.
Abstract:
Intracranial infections are the most serious and common postoperative complications with significant mortality and morbidity. Myroides odoratimimus (M. odoratimimus), a Gram-negative environmental species and an opportunistic microorganism, predominantly infects immunocompromised individuals. Limited clinical experiences and documented multidrug resistance have resulted in a scarcity of data on the treatment of M. odoratimimus infections. As far as we know, this is the first reported case of an intracranial M. odoratimimus infection with external ventricular drains (EVD) that was effectively treated with a combination of intravenous and intraventricular tigecycline in an immunocompetent adult host.
Insights
This case study reports the first successful treatment of an intracranial Myroides odoratimimus infection using tigecycline. The infection in an immunocompetent adult with external ventricular drains responded to combined intravenous and intraventricular therapy.
Area of Science:
- Infectious Diseases
- Neuroscience
- Microbiology
Background:
- Intracranial infections are severe postoperative complications with high mortality and morbidity.
- Myroides odoratimimus is an opportunistic Gram-negative bacterium often affecting immunocompromised individuals.
- Limited data exists on treating Myroides odoratimimus infections due to multidrug resistance and scarce clinical experience.
