Corneal hydrops in Terrien's marginal degeneration

Area of Science:

• Ophthalmology
• Corneal Diseases
• Ocular Surface

Background:

• Terrien's marginal degeneration is a rare, progressive thinning of the peripheral cornea.
• Complications such as rupture of Descemet's membrane are not well-documented.

Observation:

• Four cases of Terrien's marginal degeneration with spontaneous Descemet's membrane ruptures were identified.
• Corneal hydrops presented as clear intracorneal aqueous humor pockets, not stromal edema.
• Two cases exhibited peripheral pockets extending to form conjunctival filtering blebs.

Findings:

• Spontaneous Descemet's membrane rupture is a potential complication of Terrien's marginal degeneration.
• The resulting corneal hydrops can manifest as a distinct clear pocket.
• Conjunctival filtering blebs may develop from peripheral hydrops extension.

Implications:

• This presentation expands the understanding of Terrien's marginal degeneration complications.
• Conservative management may be sufficient for these specific hydrops presentations.
• Further research into the pathophysiology and optimal treatment is warranted.