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A Consensus Approach for Targeted Muscle Reinnervation in Amputees
Kyle R Eberlin1, David A Brown2, R Glenn Gaston3
1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Plastic and Reconstructive Surgery. Global Open
|April 10, 2023
Summary
Targeted muscle reinnervation (TMR) offers a new approach to managing amputation-related pain. This consensus statement provides guidelines for surgeons performing TMR to improve patient outcomes and reduce neuropathic pain.
Area of Science:
- Surgical innovation
- Pain management
- Amputee care
Background:
- Traditional amputation surgery often leads to severe residual limb and phantom limb pain.
- Neuropathic pain is a significant complication following limb amputation.
- Targeted muscle reinnervation (TMR) was developed to improve prosthesis function but is now used for pain management.
Purpose of the Study:
- To establish a consensus statement on the principles, indications, and techniques for targeted muscle reinnervation (TMR) in pain management.
- To provide a roadmap for surgeons performing TMR for neuropathic pain.
- To standardize TMR procedures and postoperative care.
Main Methods:
- Consensus statement developed by experienced surgeons specializing in TMR and neuropathic pain treatment.
- Review of existing literature and clinical experience.
- Formulation of guidelines for TMR principles, indications, technical specifics, and postoperative management.
Main Results:
- Significant variability exists in current TMR surgical approaches.
- Lack of standardized guidelines hinders consistent application of TMR.
- The consensus statement aims to address these inconsistencies.
Conclusions:
- Targeted muscle reinnervation (TMR) is increasingly recognized for its role in preventing and treating amputation-related neuropathic pain.
- Standardized guidelines are crucial for optimizing TMR outcomes.
- This consensus statement serves as a valuable resource for surgeons performing TMR.

