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Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
Patrick Chung Kay Tam1,2, Brendan Kennedy1,3, Anushia Ashokan1,3
1Departments of Infectious Diseases, Central Adelaide Local Health Network, Adelaide, South Australia.
Open Forum Infectious Diseases
|April 10, 2023
Abstract:
Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interval, .05-.51; P < .001) that was not further augmented by empiric antimicrobial choice.

