Use of Evidence-Based Vital Signs in Pediatric Early Warning Score to Predict Clinical Deterioration on Acute Care

Lisa Rickey1,2, Anqing Zhang3,4, Nathan Dean5

  • 1Division of General Pediatrics of Pediatrics, Boston Children's Hospital, Boston, MA.

Clinical Pediatrics
|April 10, 2023
PubMed

Insights

The pediatric early warning score (PEWS) using evidence-based vital signs (EBVS) enhances prediction of clinical deterioration in children. This improved tool better identifies unplanned intensive care unit transfers and patients needing critical interventions.

Area of Science:

  • Pediatric critical care medicine
  • Clinical informatics
  • Patient safety

Background:

  • The pediatric early warning score (PEWS) is a vital tool for predicting clinical deterioration in hospitalized children.
  • Current PEWS parameters rely on expert opinion, with limited published data on heart rate and respiratory rate percentiles.

Purpose of the Study:

  • To compare the effect of evidence-based vital signs (EBVS) on PEWS sensitivity and specificity for predicting unplanned intensive care unit (ICU) transfers.
  • To determine the impact of age categories on PEWS deterioration prediction.
  • To evaluate the association between EBVS PEWS and the need for invasive ICU support.

Main Methods:

  • Retrospective case-control study design.
  • Comparison of PEWS performance using standard versus EBVS parameters.
  • Logistic regression analysis to assess the association between EBVS PEWS and ICU support requirements.

Main Results:

  • EBVS PEWS demonstrated improved sensitivity (43%-71% vs. 30%-63%) for detecting unplanned ICU transfers.
  • Specificity showed a slight decrease (88%-98% vs. 93%-99%) with EBVS PEWS.
  • EBVS PEWS was significantly associated with an increased risk for requiring ICU-specific interventions (OR = 1.16, P = .0498).

Conclusions:

  • Implementing evidence-based vital signs into the PEWS can enhance its ability to identify children at risk for clinical deterioration and unplanned ICU transfers.
  • EBVS PEWS is a valuable tool for identifying patients who may require intensive care interventions, improving early recognition and management.

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