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Use of Evidence-Based Vital Signs in Pediatric Early Warning Score to Predict Clinical Deterioration on Acute Care
Lisa Rickey1,2, Anqing Zhang3,4, Nathan Dean5
1Division of General Pediatrics of Pediatrics, Boston Children's Hospital, Boston, MA.
Insights
The pediatric early warning score (PEWS) using evidence-based vital signs (EBVS) enhances prediction of clinical deterioration in children. This improved tool better identifies unplanned intensive care unit transfers and patients needing critical interventions.
Area of Science:
- Pediatric critical care medicine
- Clinical informatics
- Patient safety
Background:
- The pediatric early warning score (PEWS) is a vital tool for predicting clinical deterioration in hospitalized children.
- Current PEWS parameters rely on expert opinion, with limited published data on heart rate and respiratory rate percentiles.
Purpose of the Study:
- To compare the effect of evidence-based vital signs (EBVS) on PEWS sensitivity and specificity for predicting unplanned intensive care unit (ICU) transfers.
- To determine the impact of age categories on PEWS deterioration prediction.
- To evaluate the association between EBVS PEWS and the need for invasive ICU support.
Main Methods:
- Retrospective case-control study design.
- Comparison of PEWS performance using standard versus EBVS parameters.
- Logistic regression analysis to assess the association between EBVS PEWS and ICU support requirements.
Main Results:
- EBVS PEWS demonstrated improved sensitivity (43%-71% vs. 30%-63%) for detecting unplanned ICU transfers.
- Specificity showed a slight decrease (88%-98% vs. 93%-99%) with EBVS PEWS.
- EBVS PEWS was significantly associated with an increased risk for requiring ICU-specific interventions (OR = 1.16, P = .0498).
Conclusions:
- Implementing evidence-based vital signs into the PEWS can enhance its ability to identify children at risk for clinical deterioration and unplanned ICU transfers.
- EBVS PEWS is a valuable tool for identifying patients who may require intensive care interventions, improving early recognition and management.
Abstract:
The pediatric early warning score (PEWS) is a tool used to predict clinical deterioration. Referenced vital sign parameters are based on expert opinion but heart rate and respiratory rate percentiles in hospitalized children have been published. This retrospective case-control study of unplanned intensive care unit (ICU) transfers compares evidence-based vital signs (EBVS) effect on PEWS sensitivity and specificity, determines the impact of age categories on PEWS deterioration prediction, and evaluates whether EBVS PEWS is associated with need for invasive ICU supports. EBVS PEWS improved sensitivity (43%-71% vs 30%-63%) for unplanned transfers with slightly decreased specificity (88%-98% vs 93%-99%). Logistic regression analysis and odds ratios (ORs) demonstrated EBVS PEWS was associated with increased risk for ICU-specific supports (OR = 1.16, 95% confidence interval [CI] = 1.0-1.34, P = .0498). Evidence-based vital signs can improve PEWS sensitivity to identify unplanned ICU transfers and identify patients requiring ICU-specific interventions.
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