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Related Experiment Video

Updated: Aug 3, 2025

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging
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A Modified Technique for Interventional MRI-Guided Deep Brain Stimulation Using the ClearPoint System.

Tessa A Harland1, Jared Brougham2, Shruti Gupta3

  • 1Department of Neurosurgery, Albany Medical Center, Albany, New York, USA.

Operative Neurosurgery (Hagerstown, Md.)
|April 11, 2023
PubMed
Summary
This summary is machine-generated.

A modified surgical technique for deep brain stimulation (DBS) using MRI guidance significantly reduces procedure time and invasiveness. This refined approach maintains accuracy for DBS procedures, improving efficiency and patient outcomes.

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Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Neurological Disorders

Background:

  • Deep brain stimulation (DBS) utilizes evolving imaging-based techniques for increased efficiency and reduced invasiveness.
  • Current methods are being refined to optimize resource utilization in DBS procedures.

Purpose of the Study:

  • To describe a modified surgical technique for interventional MRI-guided stereotactic procedures using the ClearPoint system.
  • The study aimed to enhance the efficiency and reduce the invasiveness of DBS procedures.

Main Methods:

  • A modified technique was applied to 160 consecutive DBS cases for Parkinson disease, essential tremor, and dystonia.
  • Modifications included preplanning, smaller incisions, a new stereotactic frame, altered surgical steps, reduced burr hole size, minimized dural opening, and novel lead anchoring.
  • Data collected prospectively and retrospectively included radial error, procedure time, complications, and clinical outcomes.

Main Results:

  • The modified technique was used for 147 patients, with 262 leads placed, achieving an average radial error of 0.41 mm.
  • Procedure times (pin-to-stylet insertion, pin-to-frame removal, pin-to-room departure) were significantly shorter compared to the original technique (P < .0001).
  • Complications included infection (2.5%) and superficial hemorrhage (1.9%), both without permanent neurological deficits.

Conclusions:

  • The modified ClearPoint technique offers comparable accuracy to previous methods while reducing invasiveness and MRI time.
  • This refined workflow shows potential for broader applications, such as laser interstitial thermal therapy and gene delivery.