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Differential diagnosis and cause-specific treatment during out-of-hospital cardiac arrest: a retrospective
Elina Heikkilä1, Milla Jousi1, Jouni Nurmi2
1Department of Emergency Medicine and Services, University of Helsinki and University Hospital, Helsinki, Finland.
Insights
Helicopter emergency medical services frequently used ultrasound and blood tests during out-of-hospital cardiac arrest (OHCA) resuscitation. However, cause-specific treatments were administered less often, suggesting a need to improve diagnostic protocols for more effective interventions.
Area of Science:
- Emergency Medicine
- Critical Care
- Cardiology
Background:
- Cardiopulmonary resuscitation (CPR) guidelines emphasize treating reversible causes of out-of-hospital cardiac arrest (OHCA).
- The frequency of identifying and treating these causes during emergency medical services (EMS) care remains unclear.
Purpose of the Study:
- To estimate the utilization of point-of-care ultrasound and blood sample analyses during OHCA.
- To determine the frequency of cause-specific treatments administered during OHCA by EMS.
Main Methods:
- Retrospective study of 549 non-traumatic OHCA patients treated by a physician-staffed helicopter emergency medical service (HEMS) from 2016-2019.
- Data collected on the use of ultrasound, blood analyses, and specific therapies beyond standard CPR interventions.
Main Results:
- Ultrasound was employed in 60% of cases, and blood analyses in 24%.
- Cause-specific treatments were given to 15% of patients, including extracorporeal CPR, percutaneous coronary intervention, thrombolysis, and fluid resuscitation.
Conclusions:
- HEMS physicians utilized diagnostic tools like ultrasound and blood tests in 84% of OHCA cases.
- The study highlights frequent use of diagnostic methods but relatively infrequent application of cause-specific treatments, indicating a need for protocol evaluation.
Background:
The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be identified and treated. Our aim was to estimate the frequency of point of care ultrasound examinations, blood sample analyses and cause-specific treatments during OHCA.
Methods:
We performed a retrospective study in a physician-staffed helicopter emergency medical service (HEMS) unit. Data on 549 non-traumatic OHCA patients who were undergoing CPR at the arrival of the HEMS unit from 2016 to 2019 were collected from the HEMS database and patient records. We also recorded the frequency of ultrasound examinations, blood sample analyses and specific therapies provided during OHCA, such as procedures or medications other than chest compressions, airway management, ventilation, defibrillation, adrenaline or amiodarone.
Results:
Of the 549 patients, ultrasound was used in 331 (60%) and blood sample analyses in 136 (24%) patients during CPR. A total of 85 (15%) patients received cause-specific treatment, the most common ones being transportation to extracorporeal CPR and percutaneous coronary intervention (PCI) (n = 30), thrombolysis (n = 23), sodium bicarbonate (n = 17), calcium gluconate administration (n = 11) and fluid resuscitation (n = 10).
Conclusion:
In our study, HEMS physicians deployed ultrasound or blood sample analyses in 84% of the encountered OHCA cases. Cause-specific treatment was administered in 15% of the cases. Our study demonstrates the frequent use of differential diagnostic tools and relatively infrequent use of cause-specific treatment during OHCA. Effect on protocol for differential diagnostics should be evaluated for more efficient cause specific treatment during OHCA.
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