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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Related Experiment Video

Updated: Aug 3, 2025

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Patient-specific post-trigger delay in coronary CT angiography: A prospective study comparing with fixed delay.

Dian Yuan1, Yiran Wang1, Shushen Lin2

  • 1The Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, Eastern Jianshe Road, Zhengzhou 450052, Henan Province, China.

European Journal of Radiology
|April 12, 2023
PubMed
Summary

A patient-specific post-trigger delay (PTD) in Coronary CT angiography (CCTA) provides reliable scan timing and optimizes vessel opacification. This approach significantly improves image quality compared to a fixed PTD.

Keywords:
Computed tomography angiographyContrast mediaCoronary vessels

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Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Imaging Techniques

Background:

  • Coronary CT angiography (CCTA) is crucial for diagnosing coronary artery disease.
  • Optimizing contrast enhancement timing is essential for high-quality CCTA.
  • Current fixed post-trigger delay (PTD) protocols may not achieve optimal opacification for all patients.

Purpose of the Study:

  • To validate a patient-specific PTD for CCTA.
  • To compare the image quality of patient-specific PTD versus a fixed PTD in CCTA.

Main Methods:

  • A prospective study involving 204 participants randomly assigned to fixed (Group A) or patient-specific (Group B) PTD for CCTA.
  • Test bolus was used in Group B to determine reference peak enhancement timing.
  • Objective and subjective image quality assessments were performed by experienced readers.

Main Results:

  • Patient-specific PTD showed strong correlation (R=0.77) and consistency (ICC=0.618) with reference peak timing.
  • Subjective image quality was significantly better with patient-specific PTD (p < 0.001).
  • Mean vessel enhancement was higher in all coronary vessels with patient-specific PTD, with an average increase of 33.5 HU.

Conclusions:

  • Patient-specific PTD enables reliable scan timing in CCTA.
  • This individualized approach optimizes vessel opacification and enhances overall image quality.
  • Patient-specific PTD is a superior strategy for improving CCTA diagnostic performance.