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Related Experiment Videos

Postcardiotomy delirium: a critical review.

W R Dubin, H L Field, D R Gastfriend

    The Journal of Thoracic and Cardiovascular Surgery
    |April 1, 1979
    PubMed
    Summary

    Post-cardiac surgery delirium is influenced by physical health and pre-existing brain conditions, not psychological factors. Treatment involves medication, therapy, and support, with research focusing on neurotransmitters.

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    Area of Science:

    • Cardiology
    • Psychiatry
    • Critical Care Medicine

    Background:

    • Existing literature on postcardiotomy delirium presents conflicting definitions and results.
    • Understanding the multifactorial nature of postcardiotomy delirium is crucial for patient care.

    Purpose of the Study:

    • To critically review the literature on postcardiotomy delirium.
    • To identify the primary determinants of postcardiotomy delirium.
    • To evaluate the efficacy of current and proposed treatments.

    Main Methods:

    • Critical literature review of studies on postcardiotomy delirium.
    • Analysis of factors influencing delirium development and outcome.
    • Synthesis of evidence regarding therapeutic interventions.

    Main Results:

    • Cardiac status, physical illness severity, surgical complexity, and preoperative organic brain disease are key factors in postcardiotomy delirium.
    • Preoperative anxiety, denial, and depression show some correlation, while age, sex, bypass time, and psychological profile do not significantly influence outcome.
    • No consistent psychological etiology for delirium has been established; the role of preoperative interviews and sensory deprivation is equivocal.

    Conclusions:

    • Postcardiotomy delirium is primarily determined by physiological and pre-existing organic factors.
    • Effective treatment strategies include chemotherapy, psychotherapy, and environmental support.
    • Future research into biochemical abnormalities may elucidate the role of neurotransmitters in functional psychiatric disorders.

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