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Cataloguing guanidinoacetic acid content in nutritional supplements
Sergej M Ostojic1,2,3, Laszlo Ratgeber3,4, Nenad Trunic4
1Applied Bioenergetics Lab, Faculty of Sport and Physical Education University of Novi Sad Novi Sad Serbia.
Food Science & Nutrition
|April 13, 2023
Summary
Guanidinoacetic acid (GAA) from supplements is a major source of this compound, significantly exceeding levels found in other foods. This study analyzes GAA content in various nutritional supplements using NIH data.
Area of Science:
- Nutritional biochemistry
- Dietary supplement analysis
Background:
- Guanidinoacetic acid (GAA) is a naturally occurring amino acid derivative.
- GAA is found in various foods and is available in nutritional supplements.
- Anecdotal evidence suggests supplements are a primary source of GAA exposure.
Purpose of the Study:
- To summarize GAA levels in different nutritional supplements.
- To assess the contribution of supplements to overall GAA intake.
Main Methods:
- Data compilation from the U.S. National Institutes of Health (NIH) dietary supplement database.
- Analysis of GAA content across various supplement types.
Main Results:
- Nutritional supplements contain significant levels of GAA.
- Supplement-derived GAA likely out-competes dietary sources by several orders of magnitude.
Conclusions:
- Dietary supplements represent a major source of guanidinoacetic acid (GAA) exposure.
- Understanding supplement composition is crucial for assessing dietary intake of GAA.
