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Relapsed Acute Myeloid Leukemia Presenting as Multiple Breast Masses: A Case Report
Hematologic malignancy of the breast is rare. This case highlights acute myeloid leukemia (AML) relapse presenting as breast masses, emphasizing the need for thorough breast mass evaluation in patients with prior hematologic cancers.
Area of Science:
- Oncology
- Hematology
Background:
- Hematologic malignancy of the breast is exceptionally rare.
- Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow.
Observation:
- A 77-year-old female with a history of AML presented with palpable bilateral breast masses.
- Imaging revealed multiple breast masses and enlarged lymph nodes.
- Core needle biopsy and bone marrow biopsy confirmed relapsed AML and blastic plasmacytoid dendritic cell neoplasm.
Findings:
- The patient's breast masses were diagnosed as relapsed acute myeloid leukemia.
- Immunohistochemistry (IHC) was crucial in identifying leukemic markers.
Implications:
- Clinicians must consider hematologic malignancy relapse in patients with a history of such diseases presenting with breast masses.
- Prompt and accurate tissue analysis, including IHC for leukemic markers, is essential for correct diagnosis and treatment planning.
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