Related Experiment Video
Updated: Aug 2, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Reversible 'Unstable' Abdominal Angina Caused by Ruptured Plaque of the Superior Mesenteric Artery: Clinical and
Shaul Yaari1, Nurith Hiller2, Yacov Samet3
1Department of Medicine, Hadassah Hebrew University Hospital, Mount Scopus, Jerusalem, Israel.
Insights
Ruptured atheromatous plaque in mesenteric vessels can cause unstable abdominal angina, similar to unstable angina pectoris. This condition is reversible with antiplatelet medications and statins, and abdominal bruit is a key diagnostic indicator.
Area of Science:
- Vascular Medicine
- Gastroenterology
- Cardiology
Background:
- Unstable angina is linked to coronary artery disease and ruptured atheromatous plaques.
- Abdominal angina typically indicates chronic mesenteric ischemia from stable plaques.
- Ruptured atheromatous plaques are a less common cause of acute abdominal symptoms.
Purpose of the Study:
- To report the first case of unstable abdominal angina caused by a ruptured atheromatous plaque.
- To highlight the diagnostic value of epigastric bruit.
- To demonstrate the efficacy of conservative treatment.
Main Methods:
- Case report of a patient with new-onset abdominal pain.
- Diagnosis based on physical examination (epigastric bruit) and imaging (stenosis due to non-calcified atheroma).
- Treatment with aspirin and statins.
Main Results:
- A ruptured atheromatous plaque at the superior mesenteric root was identified as the cause of symptoms.
- Symptoms and epigastric bruit resolved within 3 weeks.
- Imaging showed regression of the stenotic lesion.
Conclusions:
- Ruptured atheromatous plaque in mesenteric vessels can mimic unstable angina pectoris, presenting as new-onset abdominal angina.
- This condition is potentially reversible with antiplatelet therapy and statins.
- Abdominal bruit is a valuable sign in diagnosing unexplained abdominal pain.
Abstract:
Unstable angina, characteristic of coronary artery disease, is caused by in-situ clot formation complicating ruptured atheromatous plaque. Abdominal angina, however, usually reflects chronic mesenteric ischaemia, caused by multi-vessel stable plaques involving mesenteric arteries. Herein, we describe a patient with new-onset abdominal pain caused by a ruptured atheromatous plaque at the superior mesenteric root. The diagnosis was based on an evident reversible epigastric bruit and high-degree eccentric stenosis caused by a non-calcified atheroma. Symptoms and bruit resolved within 3 weeks on aspirin and statins with regression of the stenotic lesion. Although the condition is likely common, this is the first clear-cut report compatible with 'unstable' abdominal angina, resolved by conservative treatment.
Learning Points:
Resembling unstable angina pectoris, ruptured atheromatous plaque in mesenteric vessels can develop, clinically manifested by new-onset abdominal angina.This condition may be reversible under treatment with antiplatelet medications and statins.Searching for abdominal bruit is invaluable in the assessment of unexplained abdominal pain.
More Related Videos
07:12Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
Published on: September 8, 2023
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Angina III: Clinical Manifestations and Assessment
Angina II: Classification
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease II: Pathophysiology