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An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
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An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry

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Mass spectrometry-based multi-attribute method in protein therapeutics product quality monitoring and quality control

Feng Yang1, Jennifer Zhang1, Alexander Buettner2

  • 1Pharma Technical Development, Genentech, A member of the Roche Group, South San Francisco, CA, USA.

Mabs
|April 14, 2023
PubMed

Keywords:
GMPIntact MAMLC-MSMS in QCcGMPmulti-attribute methodnew peak detectionproduct quality attributequality controltargeted attribute quantitation

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