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The evolution of gastrulation morphologies.

Guillermo Serrano Nájera1, Cornelis J Weijer2

  • 1Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK.

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Summary
This summary is machine-generated.

Embryonic gastrulation shows remarkable plasticity, allowing diverse developmental paths and evolutionary innovations. This review explores mechanisms driving this variability in vertebrates, particularly concerning yolk volume and key evolutionary transitions.

Keywords:
Cell behavioursEMTEvolutionGastrulationMorphogenesisYolk

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Area of Science:

  • Developmental Biology
  • Evolutionary Biology
  • Embryology

Background:

  • Embryonic gastrulation establishes germ layer topology but exhibits significant evolutionary variability.
  • Gastrulation morphology is not rigidly constrained, with alternative modes observed within single organisms.

Approach:

  • This review synthesizes experimental findings on vertebrate gastrulation plasticity.
  • It examines evolutionary mechanisms and the impact of yolk volume on gastrulation morphology.
  • The study provides new insights into key amniote gastrulation innovations.

Key Points:

  • Gastrulation morphology is highly variable across the animal kingdom, not rigidly evolutionarily constrained.
  • Experimental manipulation can generate alternative gastrulation modes in early embryos.
  • Yolk volume significantly influences gastrulation morphology.

Conclusions:

  • Gastrulation plasticity is a key factor in vertebrate evolution.
  • Understanding these mechanisms provides insight into developmental innovations and evolutionary transitions.