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Celecoxib alleviates nociceptor sensitization mediated by interleukin-1beta-primed annulus fibrosus cells

Junxuan Ma1, Surya Häne1,2, Janick Eglauf1,2

  • 1AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos, Switzerland.

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|April 18, 2023
PubMed
Abstract

Keywords:
3R principleAnnulus fibrosusCOX-2CelecoxibCyclooxygenase 2 inhibitorDRGDorsal root ganglionIn vitro modelInflammatory cytokineIntervertebral disk

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