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INTRAOCULAR EMULSION OF SILICONE OIL (ITEMS) GRADING SYSTEM: An Evidence-Based Expert-Led Consensus
Mario R Romano1,2, Mariantonia Ferrara3, Rosa M Coco-Martin4,5,6
1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy.
Retina (Philadelphia, Pa.)
|April 18, 2023
Summary
A new grading system, the InTraocular EMulsion of Silicone oil (ITEMS) system, was developed to assess silicone oil (SiO) emulsion in clinical settings. This system enables standardized data collection for better understanding of SiO emulsion
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Silicone oil (SiO) is frequently used as an intraocular tamponade in retinal detachment surgery.
- Assessing the presence and extent of SiO emulsion is crucial for patient outcomes.
- Current methods for detecting SiO emulsion lack standardization, hindering comparative studies.
Approach:
- A literature review was conducted by seven experts on intraocular liquid tamponades.
- A two-round Delphi method questionnaire was used to gather expert consensus on grading criteria.
- Consensus was reached on specific items for grading SiO emulsion, defined by a score of ≥7 from ≥75% of experts.
Key Points:
- The InTraocular EMulsion of Silicone oil (ITEMS) grading system was developed.
- The ITEMS system facilitates the identification of SiO microbubbles and large SiO bubbles using various ophthalmic examination techniques.
- Optical coherence tomography (OCT) is incorporated to detect SiO-associated hyperreflective dots in the macula and optic disk.
Conclusions:
- The ITEMS grading system provides a standardized, expert-validated method for assessing SiO emulsion.
- This system allows for homogenous data collection, improving the understanding of SiO emulsion's clinical relevance.
- The ITEMS system facilitates comparisons across different studies, advancing research in the field.

