TSH-stimulated increases in calcium uptake and calmodulin levels in thyroid cells

This is the first report to show that polypeptide hormone increases cellular calmodulin contents. In cultured porcine thyroid cells, 6 days' exposure to TSH (above 0.02 mU/ml) increased cellular calmodulin contents. Six days' exposure to TSH also increased calcium uptake in thyroid cells. This TSH-stimulated increase in calcium uptake was partly due to the increase in cellular calmodulin contents.