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The normal summating potential recorded from external ear canal.

A C Coats

    Archives of Otolaryngology--Head & Neck Surgery
    |July 1, 1986
    PubMed
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    This study characterizes the relationship between cochlear summating potential (SP) and auditory nerve action potential (AP) in normal hearing ears. An AP-normalized SP amplitude method offers a more accurate clinical assessment than the SP/AP ratio.

    Area of Science:

    • Audiology
    • Neuroscience
    • Biomedical Engineering

    Background:

    • Accurate clinical assessment of auditory function relies on precise electrophysiological measures.
    • The relationship between cochlear summating potential (SP) and auditory nerve action potential (AP) requires further characterization for reliable interpretation.

    Purpose of the Study:

    • To precisely characterize the SP-AP amplitude relationship in normal-hearing ears.
    • To establish confidence limits for the SP-AP relationship to define accurate clinical normal limits.
    • To evaluate novel methods for normalizing SP amplitude by AP amplitude.

    Main Methods:

    • Recorded SP and AP responses using a plastic leaf electrode on the ear canal skin surface.
    • Utilized rectangular-pulse clicks as auditory stimuli.

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  • Analyzed the linear relationship between SP and AP amplitudes across 96 normal-hearing ears.
  • Investigated log transformation to equalize SP scatter relative to AP amplitude.

    • Main Results:

    • A linear relationship was observed between SP and AP amplitudes across subjects.
    • SP amplitude scatter increased with increasing AP amplitude, which was mitigated by log transformation.
    • AP-normalized SP amplitude, derived from the distance to a log-transformed SP-AP line, proved superior to the SP/AP ratio.
    • The SP/AP ratio showed significant amplitude-dependent variations, limiting its clinical utility.

    Conclusions:

    • The across-subjects SP-AP amplitude relationship is linear and can be reliably modeled.
    • AP-normalized SP amplitude is a more robust and accurate method for adjusting SP to AP amplitude in clinical audiology.
    • This improved normalization method facilitates the establishment of more precise clinical normal limits for SP testing.