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Articles linked to this work by shared authors, journal, and citation graph.

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Novel compound heterozygous variants in <i>SIX6</i> cause a <i>PAX2</i> like Dysplastic Optic Disc with macular abnormalities without coexistent microphthalmia or cataract.

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Related Experiment Video

Updated: Aug 2, 2025

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
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Modified Nishida Procedure Combined with Lateral Rectus Disabling for Duane Retraction Syndrome.

Karthikeyan Arcot Sadagopan1,2,3,4, Ling Ding Lin5, Burton J Kushner6

  • 1Pediatric Ophthalmology & Ocular Genetics, C-MER (Shenzhen) Dennis Lam Eye Hospital, Shenzhen, China.

Journal of Binocular Vision and Ocular Motility
|April 20, 2023
PubMed
Summary
This summary is machine-generated.

This study presents a novel surgical approach for managing esotropic Duane retraction syndrome (DRS). The combined techniques aim to improve eye alignment and reduce retraction in complex cases.

Keywords:
Duane retraction syndromeY split recessionesotropiaglobe retractionlateral rectus disinsertion and periosteal fixationmodified Nishida procedurepalpebral fissure narrowing

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Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Strabismus Surgery

Background:

  • Duane retraction syndrome (DRS) is a congenital disorder affecting eye movement.
  • Surgical decisions for esotropic DRS involve multiple factors like eye alignment, retraction, and muscle contracture.

Purpose of the Study:

  • To describe a novel combination of surgical procedures for managing esotropic Duane retraction syndrome.
  • To present case studies of this new surgical approach in two patients.

Main Methods:

  • The study involved two patients with esotropic DRS.
  • Surgical interventions included medial rectus recession, lateral rectus procedures (disinsertion, periosteal fixation, Y-splitting), and modified Nishida procedures.

Main Results:

  • The first patient underwent MR recession with LR disinsertion and periosteal fixation, followed by a modified Nishida procedure.
  • The second patient received combined periosteal fixation of the LR and a modified Nishida procedure for vertical rectus muscles after prior MR recession and LR Y-splitting.

Conclusions:

  • This novel combination of surgical techniques offers a potential new management strategy for complex esotropic Duane retraction syndrome.
  • Further research is needed to evaluate the long-term efficacy of these combined procedures.