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Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
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Lateral Rectus Disabling and Simultaneous Modified Nishida Procedure for Exotropic Duane Retraction Syndrome.

Karthikeyan Arcot Sadagopan1,2,3,4, Nithya Raghunandan2, Neha Satish Saswade2

  • 1Pediatric Ophthalmology & Ocular Genetics, C-MER (Shenzhen) Dennis Lam Eye Hospital, Shenzhen, China.

Journal of Binocular Vision and Ocular Motility
|July 22, 2024
PubMed
Summary
This summary is machine-generated.

This study presents a surgical technique combining lateral rectus muscle disinsertion and periosteal fixation with the modified Nishida procedure for Exotropic-Duane Syndrome (XT-DRS). The combined approach successfully reduced key symptoms and improved convergence in patients with this congenital disorder.

Keywords:
Duane retraction syndromeY split recessionexotropiaglobe retractionlateral rectus disinsertion and periosteal fixationmodified Nishida procedurepalpebral fissure narrowing

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Area of Science:

  • Ophthalmology
  • Neurology
  • Pediatric Surgery

Background:

  • Exotropic-Duane Syndrome (XT-DRS) is a congenital disorder affecting cranial nerve innervation.
  • XT-DRS presents with exotropia, anomalous head posture, limited adduction, and globe retraction.
  • Poor convergence is common in XT-DRS due to anomalous lateral rectus muscle innervation.

Observation:

  • Two patients with XT-DRS underwent simultaneous lateral rectus muscle disinsertion and periosteal fixation (LRDAPF) and modified Nishida procedure (MNP).
  • One patient also received a contralateral lateral rectus recession.
  • Surgical outcomes were evaluated for symptom reduction and convergence improvement.

Findings:

  • The combined surgical approach led to a reduction in anomalous head posture, exotropia, globe retraction, and palpebral fissure narrowing.
  • Abnormal eye movements, including upshoot and downshoot in adduction, were also diminished.
  • Both patients demonstrated improved convergence after the surgical intervention.

Implications:

  • This surgical technique offers a potential treatment for Exotropic-Duane Syndrome, addressing multiple characteristic symptoms.
  • Improved convergence may enhance binocular function and visual outcomes for patients.
  • Further research can explore the long-term efficacy and applicability of this combined surgical approach.