Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stress granule phase separation in stress-responsive cytosolic extract-in-oil droplets.

Nature communications·2026
Same author

Metal-Coordinated His-Tag Functionalization of Polymeric Nanogels for Therapeutic Applications.

ACS applied nano materials·2026
Same author

Bottlebrush Polymers for Multiphoton 3D Laser Printing.

ACS macro letters·2026
Same author

A printable, unimolecular, core-shell polymer bottlebrush-based signal transducer using solvatochromatic reporting.

Chemical science·2025
Same author

nano-FFA: ink formulation and process optimization in multiphoton 3D laser printing using full factorial analysis.

Nanoscale·2025
Same author

Ultrabroadband plug-and-play photonic tensor core packaging with sub-dB loss.

Science advances·2025
Same journal

Anion-Engineered Organic Electrochemical Transistors With Multi-Timescale Synaptic Dynamics for Task-Adaptive Spiking Neural Networks.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Dimensional Effect on the Lattice Anharmonicity in Graphene and Graphite.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

A Modular Core-Shell Nanoparticle Platform for Dual-Modal MRI-Luminescence With High Relaxivity.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Highly Selective Construction of D<sub>2</sub>-Symmetric Chiral Carbon Nanorings and the Diverse Assembly With Fullerenes.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

A Synergistic Process Optimization and Data-Driven Modeling Strategy for Unraveling and Enhancing the Low-Light Response in Back-Contact Solar Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Porous Hydrogel-Mediated One-Step Selection of Mannoprotein-Targeted Aptamers for Early Diagnosis of Invasive Saccharomyces cerevisiae Infections.

Small (Weinheim an der Bergstrasse, Germany)·2026
See all related articles

Related Experiment Video

Updated: Aug 2, 2025

Micro-masonry for 3D Additive Micromanufacturing
08:45

Micro-masonry for 3D Additive Micromanufacturing

Published on: August 1, 2014

10.5K

Macromolecular Engineering: From Precise Macromolecular Inks to 3D Printed Microstructures.

Samantha O Catt1, Maximillian Hackner1,2, Joachim P Spatz1,2

  • 1Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM) and Organic Chemistry Institute (OCI), Heidelberg University, 69120, Heidelberg, Germany.

Small (Weinheim an Der Bergstrasse, Germany)
|April 20, 2023
PubMed
Summary
This summary is machine-generated.

Sequence-defined macromolecules offer precise control for synthetic materials. This study explores their use as printable inks, demonstrating sequence impacts printability and material properties for advanced 3D printing applications.

Keywords:
laser lithographymacromolecular engineeringmechanical propertiessequence-defined polymerstwo-photon

More Related Videos

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

12.5K
Interlinked Macroporous 3D Scaffolds from Microgel Rods
07:32

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

2.2K

Related Experiment Videos

Last Updated: Aug 2, 2025

Micro-masonry for 3D Additive Micromanufacturing
08:45

Micro-masonry for 3D Additive Micromanufacturing

Published on: August 1, 2014

10.5K
Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

12.5K
Interlinked Macroporous 3D Scaffolds from Microgel Rods
07:32

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

2.2K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Additive Manufacturing

Background:

  • Nature features complex macromolecules, but synthetic control is limited.
  • Sequence-defined polymers offer precise control over macromolecular structure.
  • Applications of sequence-defined macromolecules, especially in printable materials, are largely unexplored.

Purpose of the Study:

  • To investigate the rational design of precise macromolecular inks for 3D microprinting.
  • To explore the impact of macromolecular sequence on printability and material properties.
  • To establish sequence-defined macromolecules as a new class of functional materials for 3D printing.

Main Methods:

  • Synthesis of three sequence-defined oligomers with varying crosslinker placement (alternating, triblock, block).
  • Utilizing two-photon laser printing for 3D microfabrication of the synthesized oligomers.
  • Characterization of the printed materials to assess printability and final properties.

Main Results:

  • Demonstrated successful synthesis and 3D microprinting of sequence-defined oligomers.
  • Established that macromolecular sequence critically influences printability.
  • Showed that the positioning of crosslinkable units dictates the final properties of the printed material.

Conclusions:

  • Precise sequence control in synthetic macromolecules is achievable.
  • Sequence-defined macromolecules can be rationally designed as printable inks.
  • This work opens new avenues for next-generation functional materials in 3D printing.