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Effects of exercise on depression in patients with rheumatic diseases: a systematic review and meta-analysis
Yanfeng Bao1,2, Qian Liang2,3,4, Juan Ji2
1Nanjing University of Traditional Chinese Medicine, 210023, Nanjing, China.
Objective:
To assess the effects of exercise intervention on depression in rheumatic diseases by means of a meta-analysis.
Methods:
The Cochrane Library, Embase, Medline, PubMed, and relevant records were searched. The qualities of randomized controlled trials were evaluated. Meta-analysis of the obtained related data was completed using RevMan 5.3. Heterogeneity was also evaluated with χ2 test and I2.
Results:
Twelve RCTs were reviewed. Compared with baseline, the meta-analysis results showed that there was significant difference in the improvement of depression assessed by HADs, BDI, CES‑D, and AIMS in patients with rheumatic diseases (post exercise vs. baseline, -0.73 [-1.05, -0.4], P < 0.0001, I2 = 0%). In subgroup analysis, although none of these trends in BDI and CES‑D subgroups were significant at P < 0.05, there were clear trends towards improvement in depression.
Conclusion:
As an alternative or supplementary treatment, the effect of exercise on rheumatism is obvious. Rheumatologists can consider exercise as an integral part of the treatment of patients with rheumatism.
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