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Updated: Aug 2, 2025

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Venous anomalies and thromboembolism
Caroline Dix1, Warren Clements2, Harry Gibbs3
1Department of Clinical Haematology, The Alfred Hospital, Melbourne, VIC, 3004, Australia. caroline_dix@hotmail.com.
Patients with venous anomalies face higher risks of venous thromboembolism (VTE) and complications. Recognizing these often-overlooked conditions is key for appropriate management and preventing recurrence.
Area of Science:
- Vascular Medicine
- Radiology
- Thrombosis Research
Background:
- Venous anomalies are frequently under-recognized contributors to venous thromboembolism (VTE).
- These anatomical variants disrupt venous flow, causing hypertension, reduced velocity, and turbulence, thereby increasing VTE risk.
- Unlike unprovoked VTE, anatomical causes are less frequently investigated.
Purpose of the Study:
- To highlight the significance of recognizing venous anomalies in patients with VTE.
- To present cases and radiological findings of May-Thurner syndrome (MTS), inferior vena cava (IVC) variants, and venous aneurysms.
- To review current literature on the optimal diagnosis and management of these venous anomalies.
Main Methods:
- Case series presentation with representative radiological images.
- Literature review focusing on diagnosis and management strategies.
- Analysis of risk factors associated with venous anomalies and VTE.
Main Results:
- Venous anomalies predispose individuals to extensive VTE and severe post-thrombotic syndrome (PTS).
- Patients with venous anomalies have a high rate of VTE recurrence if anticoagulation is discontinued.
- Endovascular or surgical interventions may be appropriate management options.
Conclusions:
- Early recognition of venous anomalies is crucial for effective VTE management.
- Understanding these conditions can guide appropriate diagnostic and therapeutic interventions.
- Addressing venous anomalies can mitigate the risk of VTE recurrence and severe PTS.
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