Primary Gastric Rhabdomyosarcoma.

Area of Science:

• Gastroenterology
• Oncology
• Pathology

Background:

• Primary gastric rhabdomyosarcoma is an exceptionally rare malignancy.
• Rhabdomyosarcoma typically originates in skeletal muscle, making gastric involvement uncommon.

Observation:

• An 87-year-old male presented with abdominal pain.
• Computed tomography (CT) and 18F-fluorodeoxyglucose positron emission tomography-CT identified a large tumor in the stomach's muscularis propria.
• Splenic vein tumor thrombosis was also detected.

Findings:

• Endoscopic ultrasound-guided fine-needle aspiration and biopsy confirmed the diagnosis.
• The tumor's origin from the muscularis propria of the stomach was established.

Implications:

• This case highlights the importance of considering rare diagnoses in the differential for gastric masses.
• Accurate diagnosis through advanced imaging and biopsy is crucial for appropriate management of gastric rhabdomyosarcoma.
• Further research into the etiology and treatment of primary gastric rhabdomyosarcoma is warranted.