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Management of children with hemophilia A on emicizumab who need surgery

Mark Belletrutti1, Mihir Bhatt2, Nasrin Samji2

  • 1BC Children's Hospital, Oncology/Hematology/BMT, University of British Columbia, Vancouver, BC, Canada.

Frontiers in Pediatrics
|April 21, 2023
PubMed

The introduction of emicizumab into the treatment regime of persons with hemophilia A has dramatically reduced frequency of bleeding in patients with and without inhibitors. However, in children with Hemophilia A (CwHA) who require surgical or other invasive procedures, additional treatment with factor replacement or other hemostatic agents may still be needed to prevent intraoperative or postoperative bleeding. This review will look at the reported outcomes in CwHA on emicizumab who have had surgery and propose recommendations for the best perioperative management of major and minor procedures.

Keywords:
bleedingemicizumabhemophilia Apediatricsurgery

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