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Updated: Aug 2, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Dermatofibrosarcoma Protuberans of the Face
Daniel Pardo1, Danielle Scarola2, Gillian K Weston3
1University of Connecticut School of Medicine, Farmington, CT, USA.
Abstract:
Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive tumor with high rate of local recurrence but low metastatic potential. Its high-grade fibrosarcomatous variant and occurrence on the head and neck are rare findings associated with increased morbidity and mortality. The most significant prognostic feature of DFSP is obtaining tumor free surgical margins. As such, accurate recognition and proper management of this uncommon and locally aggressive malignancy is especially crucial in head and neck surgery.
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