Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Ventilation: Inhalation01:24

Pulmonary Ventilation: Inhalation

4.1K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
4.1K
Pulmonary Function Tests01:25

Pulmonary Function Tests

397
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
397
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

758
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
758
Pressure Relationships in Thoracic Cavity01:24

Pressure Relationships in Thoracic Cavity

2.7K
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
2.7K
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.0K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.0K
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

1.7K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HIgh versus STAndard blood Pressure target in hypertensive high-risk patients undergoing elective major abdominal surgery: the HISTAP multicenter randomized clinical trial.

Intensive care medicine·2026
Same author

Measured Versus Predicted Prosthesis-Patient Mismatch after TAVR in Sievers Type 1 BAV: Incidence, Determinants, and Outcomes From the AD-HOC Registry.

Circulation. Cardiovascular interventions·2026
Same author

Effect of Weight-based versus Absolute Norepinephrine Dosing on Mortality Risk in Obese Patients with Septic Shock: An Observational, Multicohort, Retrospective Study.

Anesthesiology·2026
Same author

Decoding MRI Presentation of Primary Central Nervous System Diffuse Large B Cell Lymphoma: A Novel Subgroup Perspective.

AJNR. American journal of neuroradiology·2026
Same author

Intraoperative blood pressure management in noncardiac surgery: a narrative review based on current evidence.

Intensive care medicine·2026
Same author

Current perspectives in cardiogenic shock.

Journal of critical care·2026
Same journal

Cardiogenic shock - toward phenotype-directed, precision management.

Current opinion in critical care·2026
Same journal

The future of critical care nutrition: from calorie counting to precision personalized metabolism therapy.

Current opinion in critical care·2026
Same journal

Editorial introduction.

Current opinion in critical care·2026
Same journal

Generative artificial intelligence for outcome prediction in critical care: the future is now?

Current opinion in critical care·2026
Same journal

Feeding under support in critical care illness: metabolic and nutritional management during extracorporeal membrane oxygenation and continuous renal replacement therapy.

Current opinion in critical care·2026
Same journal

Multinational collaborations in critical care research: feasible and useful?

Current opinion in critical care·2026
See all related articles

Related Experiment Video

Updated: Aug 2, 2025

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

772

Transpulmonary thermodilution.

Antonio Messina1,2, Valeria Alicino1, Maurizio Cecconi1,2

  • 1IRCCS Humanitas Research Hospital, Via Manzoni, Rozzano.

Current Opinion in Critical Care
|April 21, 2023
PubMed
Summary
This summary is machine-generated.

Transpulmonary thermodilution (TPTD) offers reliable hemodynamic monitoring for critically ill patients. This technique assesses cardiac output and fluid status, aiding in optimized fluid resuscitation and avoiding overload.

More Related Videos

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.5K
Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome ARDS
07:20

Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome ARDS

Published on: September 7, 2016

11.3K

Related Experiment Videos

Last Updated: Aug 2, 2025

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

772
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.5K
Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome ARDS
07:20

Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome ARDS

Published on: September 7, 2016

11.3K

Area of Science:

  • Critical care medicine
  • Cardiopulmonary monitoring
  • Hemodynamic assessment

Background:

  • Hemodynamic monitoring is crucial for managing acutely ill patients, aiming to optimize cardiac output (CO) and tissue oxygen delivery.
  • Transpulmonary thermodilution (TPTD) is an advanced, multiparametric technique for cardiopulmonary monitoring.
  • TPTD provides insights into both cardiac function and thoracic fluid distribution.

Approach:

  • Systematic review and critical assessment of existing data on TPTD.
  • Detailed description of TPTD technical aspects and methodologies.
  • Appraisal of TPTD-derived parameters in various clinical settings.

Key Points:

  • TPTD enables comprehensive cardiopulmonary assessment beyond CO estimation.
  • Integration with arterial pulse contour analysis allows continuous CO monitoring and fluid responsiveness assessment.
  • TPTD-derived indices, including extravascular lung water (EVLW) and pulmonary vascular permeability index (PVPI), guide fluid management.

Conclusions:

  • TPTD is a valuable, albeit invasive, tool for advanced hemodynamic monitoring.
  • TPTD-guided algorithms can optimize fluid resuscitation and prevent fluid overload.
  • The technique provides crucial data for clinical decision-making in critical care settings.